A uracil nucleotide containing a pyrophosphate group esterified to C5 of the sugar moiety.

Isolated from Bacillus megaterium; intermediate in the biosynthesis of galactosamine-6-phosphate polymer.

A nucleoside diphosphate sugar which can be epimerized into UDPglucose for entry into the mainstream of carbohydrate metabolism. Serves as a source of galactose in the synthesis of lipopolysaccharides, cerebrosides, and lactose.

A key intermediate in carbohydrate metabolism. Serves as a precursor of glycogen, can be metabolized into UDPgalactose and UDPglucuronic acid which can then be incorporated into polysaccharides as galactose and glucuronic acid. Also serves as a precursor of sucrose lipopolysaccharides, and glycosphingolipids.

A nucleoside diphosphate sugar which serves as a source of glucuronic acid for polysaccharide biosynthesis. It may also be epimerized to UDP iduronic acid, which donates iduronic acid to polysaccharides. In animals, UDP glucuronic acid is used for formation of many glucosiduronides with various aglycones.

Encoded by UGT1 complex which encodes human bilirubin, phenol, and other UDP-glucuronosyltransferase isozymes with identical carboxyl termini; RefSeq NM_000463 (human).

Catalyzes bile acid glucuronidation at high rates exclusively at the carboxyl moiety.

Conjugates one or two glucuronic acid molecules to the carboxyl groups of the propionate side chains of bilirubin thereby removing free bilirubin from the body; UGT1.4 is the minor human bilirubin UDP-glucuronosyltransferase (UGT).

RefSeq NM_205862.

Induced by 3-methylcholanthene in rat hepatoma cells.