Dust, steelmaking
TSCA Definition 2019: The dust generated during the charging, operation, and tapping of a steelmaking furnace and from steel conditioning, including that which is recovered through the use of pollution abatement equipment. Composed primarily of iron oxides. May contain varying amounts of other metallic oxides and trace compounds.
Dutasteride
A 5-ALPHA-REDUCTASE INHIBITOR that is reported to inhibit both type-1 and type2 isoforms of the enzyme and is used to treat BENIGN PROSTATIC HYPERPLASIA.
Duteplase
Recombinant form of the naturally occuring tissue-type plasminogen activator; administered in double-chain form unlike Alteplase which is predominantly single chain.
Dutimelan
Plurichronocorticoid administered at 8 hours & 15 hours; contains prednisolone acetate & cortisone acetate.
Dutogliptin
An orally available, potent, and selective di-peptidyl peptidase 4/DPP4 inhibitor that improves glycemic control in type 2 diabetic patients.
Dutomycin
Isolated from Streptomyces.
Duvelisib
NCI: An orally bioavailable, highly selective and potent small molecule inhibitor of the delta and gamma isoforms of phosphoinositide-3 kinase (PI3K) with potential immunomodulating and antineoplastic activities. Upon administration, duvelisib prevents the activation of the PI3K delta/gamma-mediated signaling pathways which may lead to a reduction in cellular proliferation in PI3K delta/gamma-expressing tumor cells. Unlike other isoforms of PI3K, the delta and gamma isoforms are overexpressed primarily in hematologic malignancies and inflammatory and autoimmune diseases. By selectively targeting these PI3K isoforms, PI3K signaling in normal, non-neoplastic cells is minimally or not affected which would result in a more favorable side effect profile.
Duvoglustat
An alpha-glucosidase inhibitor with antiviral action. Derivatives of deoxynojirimycin may have anti-HIV activity.