Dapsone

Formula : C12-H12-N2-O2-S
CAS : 80-08-0 
F 1358 1358F 4-13-00-01306 (Beilstein Handbook Reference) AI3-08087 p-Aminophenyl sulfone Aniline| 4|4'-sulfonyldi- Avlosulfon Avlosulfone Avlosulphone Benzenamine| 4|4'-sulfonylbis- Bis(p-aminophenyl) sulfone Bis(4-aminophenyl) sulfone Bis(p-aminophenyl)sulphone Bis(4-aminophenyl)sulphone BRN 0788055 CCRIS 192 Croysulfone Croysulphone DADPS Dapson Dapsona Dapsona [INN-Spanish] Dapsone Dapsonum Dapsonum [INN-Latin] DDS DDS (pharmaceutical) Diaminodifenilsulfona [Spanish] 4|4-Diaminodifenylsulfon [Czech] Diaminodiphenyl sulfone p|p'-Diaminodiphenyl sulfone Diamino-4|4'-diphenyl sulfone p|p-Diaminodiphenyl sulphone Diamino-4|4'-diphenyl sulphone Di(p-aminophenyl) sulfone Di(4-aminophenyl) sulfone Di(4-aminophenyl)sulfone Di(p-aminophenyl)sulphone Di(4-aminophenyl)sulphone Diaphenylsulfon Diaphenylsulfone Diaphenylsulphon Diaphenylsulphone Diphenasone N|N'-Diphenyl sulfondiamide Diphone Disulone DSS DSS (VAN) Dubronax Dumitone EINECS 201-248-4 Eporal HSDB 5073 Metabolite C NCI-C01718 Novophone NSC-6091 NSC 6091D Sulfadione Sulfona Sulfona-Mae Sulfone| diphenyl| 4|4'-diamino- Sulfone UCB 1|1'-Sulfonylbis(4-aminobenzene) 4|4'-Sulfonylbisaniline p|p-Sulfonylbisbenzamine 4|4'-Sulfonylbisbenzamine p|p-Sulfonylbisbenzenamine 4|4'-Sulfonylbisbenzenamine p|p'-Sulfonyldianiline 4|4'-Sulfonyldianiline Sulphadione 1|1'-Sulphonylbis(4-aminobenzene) p|p-Sulphonylbisbenzamine 4|4'-Sulphonylbisbenzamine p|p-Sulphonylbisbenzenamine 4|4'-Sulphonylbisbenzenamine Sulphonyldianiline p|p-Sulphonyldianiline 4|4'-Sulphonyldianiline Sumicure S Tarimyl Udolac WR 448 HY 976 HT 976 Hardener HT 976 4|4'-Dapsone 4|4'-Diaminodiphenyl sulfone 4|4'-Diaminodiphenyl suphone Araldite HT 976 4-Aminophenyl sulfone Aczone NSC 6091 4|4-Diaminodifenylsulfon Diaminodifenilsulfona UNII-8W5C518302 EC 201-248-4

A sulfone active against a wide range of bacteria but mainly employed for its actions against MYCOBACTERIUM LEPRAE. Its mechanism of action is probably similar to that of the SULFONAMIDES which involves inhibition of folic acid synthesis in susceptible organisms. It is also used with PYRIMETHAMINE in the treatment of malaria. (From Martindale, The Extra Pharmacopoeia, 30th ed, p157-8)