Methoxy polyethylene glycol-epoetin beta
Formula :
CAS :
677324-53-7
UNII-LR3UXN0193
1-165-Erythropoietin (human)| monamide with alpha-(3-carboxypropyl)-omega-methoxypoly(oxy-1|2-ethanediyl)
CERA
CERA [WHO-DD]
Methoxy polyethylene glycol-epoetinbeta [EMA EPAR]
Methoxy polyethylene glycol-epoetinbeta [MART.]
Mircera
Pegzerepoetin alfa
Pegzerepoetin alfa [WHO-DD]
Continuous erythropoietin receptor activator
HSDB 8219
A third-generation erythropoietic beta molecule created by integrating a large polymer chain into the molecule, thus increasing the molecular weight to twice that of epoetin at approximately 60 kDa; the methoxy-polyethylene glycol polymer chain is integrated via amide bonds between the N-terminal amino group or the e-amino group of lysine (predominantly lysine-52 or lysine-45), using a single succinimidyl butanoic acid linker; an erythropoiesis-stimulating agent for the treatment of anemia.