Brivanib
Formula : C19-H19-F-N4-O3
CAS :
649735-46-6
A prodrug of BMS-540215.
Brivanib alaninate
Formula : C22-H24-F-N5-O4
CAS :
649735-63-7
NCI: The alaninate salt of a vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with potential antineoplastic activity. Brivanib strongly binds to and inhibits VEGFR2, a tyrosine kinase receptor expressed almost exclusively on vascular endothelial cells; inhibition of VEGFR2 may result in inhibition of tumor angiogenesis, inhibition of tumor cell growth, and tumor regression. (NCI Thesaurus)