Dactinomycin
Formula : C62-H86-N12-O16
CAS :
50-76-0
X 97
ACT [antibiotic]
ACT D
Actinomycin C1
Actinomycin D
Actinomycin I
Actinomycin I1
Actinomycin X 1
Actinomycin 7
Actinomycin 11 cosmegen
Actinomycin A IV
Actinomycin Aiv
Actinomycin IV
Actinomycin C(sub1)
Actinomycin I(sub 1)
Actinomycindioic D acid| dilactone
Actinomycin-(threo-val-pro-sar-meval)
Acto-D
AD (VAN)
AI3-26374
Antibiotic from Streptomyces parvullus
CCRIS 9
Chounghwamycin B
Cosmegen
Dactinomicina [INN-Spanish]
Dactinomycin
Dactinomycin D
Dactinomycine [INN-French]
Dactinomycinum [INN-Latin]
Dilactone actinomycin D acid
Dilactone actinomycindioic D acid
EINECS 200-063-6
HBF 386
HSDB 3220
Lyovac cosmegen
Meractinomycin
NCI-C04682
NSC 3053
Oncostatin K
3H-Phenoxazine-1|9-dicarboxamide| 2-amino-N|N'-bis(hexadecahydro-2|5|9-trimethyl-6|13-bis(1-methylethyl)-1|4|7|11|14-pentaoxo-1H-pyrrolo(2|1-i)(1|4|7|10|13)oxatetra-azacyclohexadecin-10-yl)-4|6-dimethyl-3-oxo-
Stereoisomer of N|N'-((2-amino-4|6-dimethyl-3-oxo-3H-phenoxazine-1|9-diyl)bis(carbonylimino(2-(1-hydroxyethyl)-1-oxo-2|1-ethanediyl)imino(2-(1-methylethyl)-1-oxo-2|1-ethanediyl)-1|2-pyrrolidinediylcarbonyl(methylimino) (1-oxo-2|1-ethanediyl)))bis(N-methyl-L-valine)di-xi-lactone
Dactinomicina
Dactinomycine
Dactinomycinum
UNII-1CC1JFE158
Cosmegen Lyovac
Lyovac-Cosmegen
A compound composed of a two CYCLIC PEPTIDES attached to a phenoxazine that is derived from STREPTOMYCES parvullus. It binds to DNA and inhibits RNA synthesis (transcription), with chain elongation more sensitive than initiation, termination, or release. As a result of impaired mRNA production, protein synthesis also declines after dactinomycin therapy. (From AMA Drug Evaluations Annual, 1993, p2015)